lyme arthritis radiology

Although the pathogenesis of Lyme arthritis is complex and still under study, the clinical presentation and natural history have been established by long-term observation of … How it is different from fibromyalgia: Stiffness is typically confined to the neck in Lyme … While the skin, the central nervous system, the heart, the eye and other organs may be the target of infection with Borrelia burgdorferi, joints are the exclusive target in most cases of Lyme arthritis. J Rheumatol 2019; 46:871. If you have them, you may wonder which condition you have. Comment goes here. Symptoms can occur in connective tissue. Lyme disease patients often struggle with ongoing symptoms including arthritis. Lyme arthritis typically involves less than 5 joints and they typically are large joints such as the knee. Just a few miles away a … If Lyme disease isn't treated, around 60 per cent of patients will develop symptoms similar to arthritis. 11 (The knee was involved in 90% of cases.) To determine whether second-line intraarticular glucocorticoid (IAGC) injection improves outcomes in children with persistently active Lyme arthritis after initial antibiotics. Osteoarthritis 2. Lyme artritis is een vorm van infectieuze artritis veroorzaakt door Borrelia burgdorferi (de ziekte van Lyme). One of the most common Lyme disease misdiagnoses is Rheumatoid Arthritis (RA), a chronic condition with less clear causes than Lyme disease. MENKES Clinique de Rhumatologie et Service de Rhumatologie A, Hital Cochin, 27 rue du Faubourg Saint Jacques, 75674 Paris, France (Received 6 March 1989; accepted ll April 7989) Summary - Evanescent arthralgias and myalgias are common early symptoms of Lyme … Excessive up-regulation of the inflammatory process has been shown in patients with antibiotic-refractory Lyme arthritis. Antibody-based Lyme disease tests have excellent sensitivity in patients with Lyme arthritis. Als de ziekte meer dan een jaar aanwezig is, dan wordt dit late Lymeziekte genoemd. SIGNS / EXAM FINDINGS: Physical findings in osteoarthritic joints include bony enlargement, crepitus, cool effusions, and decreased range of motion. + lyme arthritis radiology 28 Apr 2021 Initial symptoms of elbow arthritis include pain and stiffness around the elbow, as well as swelling. Posttreatment Lyme disease syndromes: distinct pathogenesis caused by maladaptive host responses. CONCLUSION. It has been theorized that once the microorganism from a Lyme infection moves to the joints, the immune response against it cross-reacts with one's own joint tissue in people who have HLA-DR4 and HLA-DR2, leading to an autoimmune reaction and … Lyme Lyme disease can result in intermittent attacks of arthritis in a few large joints. Stage 1: Early localized disease that may present with erythema migrans and alow grade fever. Outcomes were also similar between intravenous (IV) and oral antibiotic-treated cohorts, but older children seemed to respond more favorably to IV therapy. Treatment of Lyme Arthritis. Intravenous ceftriaxone: 2 g twice per day or 4 g once per day for 21 days (when an oral switch is being considered, use doxycycline) Oral doxycycline: 200 mg twice per day or 400 mg once per day for 21 days. Lyme arthritis more often than not occurs in the knees, but it can also affect other large joints, including the shoulder, elbow, ankle, jaw, wrist, and hip. Genetics, diet and lifestyle are determinants of osteoporosis. In addition, patients with Lyme arthritis usually lack fever or systemic symptoms. Of 25 patients with severe arthritic manifestations the most frequent radiographic finding was knee joint effusion. Lyme disease, while still an uncommon disease in the UK, is on the increase. Arthritis is a frequent manifestation of Lyme disease. Prevalence of ArthritisPrevalence of Types of Arthritis * 2005 available data) 46 Million Diagnosed Author Information. This pain can appear in any joint on the body. An estimated 300,000 new cases occur every year. Rheumatoid arthritis (RA) and Lyme disease are very different conditions that need separate treatments. 9,10 A normal cell count is <500 cells/mm 3 and, in patients with osteoarthritis or septic arthritis… New study focused on people with Lyme arthritis, but findings may apply to chronic symptoms of the tick-borne disease. Because of the clinical signs caused by Lyme Disease, vaccination may be recommended by some veterinarians. Lyme disease arthritis. 1 Management (arthritis) 1.1 Review question: What is the most clinically and cost-effective treatment for people with arthritis related to Lyme disease? Post-Treatment Lyme Disease Syndrome. Seronegative arthritis (ankylosing spondylitis, reactive arthritis, psoriatic arthritis, enteropathic… Gout is a very painful type of arthritis that usually affects the lower extremities. We wanted to identify MRI features that may distinguish Lyme arthritis from septic arthritis in children. The research was conducted at Virginia Tech, US. Qualitative assessment shows that the characteristics of the disease in Germany do not differ fundamentally from those reported in the USA. Arthritis is one of the most prominent features of Lyme disease, the tick-borne illness caused by Borrelia burgdorferi. Lyme disease in the U.S. is caused by a form of bacteria, the spirochete Borrelia burgdorferi, infecting humans by tick bites. A small percentage of people get a disabling chronic type of arthritis that most often affects the knees. Treatment. The primary objective of this study was to determine whether patients with putative late-onset Lyme arthritis based upon synovial fluid Borrelia burgdorferi IgM and IgG immunoblot testing offered by commercial laboratories satisfied conventional criteria for the diagnosis of Lyme arthritis. While it’s highly prevalent in New England, Lyme disease has been reported in every state, and its … Lyme disease affecting the central nervous system. Lyme arthritis is widespread in the United States, where it is estimated to affect 33% of patients with Lyme disease, 8 and in Europe, where estimates of infection range between 3% and 15%. Lyme Arthritis Duration Rheumatoid Radiology Shoulder. Lyme arthritis Kia Katchar1,2, Elise E Drouin1 and Allen C Steere1* Abstract Introduction: Natural killer (NK) and natural killer T (NKT) cells provide a first line of defense against infection. Of 25 patients with severe arthritic manifestations the most frequent radiographic finding was knee joint effusion. Infection by the spirochete Borrelia burgdorferi, if left untreated, can lead to a form of Lyme disease called Lyme arthritis. Lyme arthritis affects big joints like the knee and only shows up on one side. Intra-Articular Glucocorticoid Injection Safe for Pediatric Lyme Arthritis. METHODS: Patients were randomly assigned to treatment with doxycycline or amoxicillin plus probenecid for 30 days. Arthritis & Rheumatism. lyme arthritis radiology + lyme arthritis radiology 29 Mar 2021 Painful and swollen joints. LYME, Conn. — A teenage boy suddenly developed severe pains in his leg and could not walk. Lyme arthritis of right knee Microscopic (histologic) description Chronic papillary synovitis with hyperplasia, fibrin deposition, mononuclear cell infiltrates, onion skin thickening of arterial walls; resembles rheumatoid arthritis Know what is lyme arthritis, its occurrence, diagnosis, treatment and prevention. 2.1 Classification of arthritis 1. It is a prevalent symptom of Lyme disease and can occur in the early or late stages of Lyme. In addition, the data did not show a temporal spike in arthritis diagnoses after the second and third vaccine dose expected for an … Patients may note pain and inflammation in connective tissue like tendons, ligaments, and bursae. Borelia bacteria attacks the connective tissue in the joints leading to inflammation, pain and consequent degeneration of the joints. My personal approach involves consideration of each of the following five principles in turn: Sutton’s law. Lyme neuroborreliosis (LNB) is neurologic involvement secondary to systemic infection by the spirochete Borrelia burgdorferi in the United States and by … The term is often used by the public to indicate any disease involving pain or stiffness of the musculoskeletal system. Treatment. 12 hours ago Delete Reply Block. Because its symptoms mimic those of so many other diseases – both tick-borne and otherwise – Lyme disease is often misdiagnosed. Rheumatology > Arthritis First Case of Lyme Arthritis Documented in Prosthetic Knee — Symptoms started 10 months after joint arthroplasty. Lyme arthritis affects one or more joints in the body. Spondylolisthesis and vertebral fracture were significantly more prevalent in patients with rheumatoid arthritis (RA) than in the general population, according to study findings published in the Spine Journal. This is to Learn, Search, for treatments involving Autoimmune conditions, Arthritis,Candida,Lupus, SS, MS, IBS, and more new treatments and ones overlooked, (MEDICAL DISCLAIMER: All information is intended for your general knowledge only and is not a substitute for … Section Editor (s): Pollock, Avrum N. MD, FRCPC. Spirochetes are transmitted to horses by infected ticks. It contains: Information about radiology tests and procedures that you or a family member may require. Pattern approach. What are synonyms for Lyme arthritis? Chan, Sherwin S. MD, PhD *; Pollock, Avrum N. MD, FRCPC †. 2004. Because Lyme arthritis is a late manifestation of untreated Lyme disease, high levels of anti-Borrelial antibodies are present & serology is a highly sensitive test. Not all infected horses develop clinical signs of Lyme disease. Don’t panic if you learn you have rheumatoid arthritis.While there is no cure, people are living better now with RA than ever before. Qualitative assessment shows that the characteristics of the disease in Germany do not differ fundamentally from those reported in the USA. While many patients with Lyme arthritis respond well to antibiotic therapy, other patients can experience post-infectious antibiotic-refractory arthritis. Deformity in the hands. MicroRNA-146a provides feedback regulation of lyme arthritis but not carditis during infection with Borrelia burgdorferi. However, these cells have not yet been examined in patients with Lyme arthritis, a late disease manifestation. Steere AC. Often in the knees, Lyme arthritis is a common late symptom of Lyme disease. Symptoms of Lyme Disease. Because few synovial samples have yet been analysed by species-specific DNA amplification methods, further studies are needed to define the spectra of clinical manifestations associated with these different species. Arthritic symptoms in dogs come on slowly and never improve on their own; they only get worse with time. Rheumatoid arthritis 3. Weeks to months following the onset of Lyme borreliosis, a histopathological reaction characteristic of synovitis including bone, joint, muscle, or tendon pain may occur. While knees are a hallmark manifestation, other joints like the wrist, ankle, elbow, and shoulder can be affected, too. Due to their similar presentation, Lyme arthritis and septic arthritis are difficult to differentiate. In fewer cases, other joints may be affected including the shoulders, wrists, hips, elbows and ankles. However, even complex cases will usually yield to a logical and systematic approach. Many rheumatic diseases can mimic Lyme arthritis such as rheumatoid arthritis, septic arthritis, gout, pseudogout, reactive arthritis, juvenile idiopathic arthritis, psoriatic arthritis. Sometimes people get diagnosed with fibromyalgia. The arthritis may be migratory or intermittent, particularly initially, as well as persistent. Lyme arthritis diagnosis. Even though doctors aren’t testing for peptidoglycan quite yet, they can test joint fluid for neutrophils (a type of white blood cell), mild to moderate inflammation and get a white blood cell count to figure out if your arthritis is Lyme-related. Lyme disease is a newly recognized, multi-system disorder that may be associated with chronic arthritis. Lyme disease is caused by infection with the bacterium Borrelia burgdorferi.Although most cases of Lyme disease can be cured with a 2- to 4-week course of oral antibiotics, patients can sometimes have symptoms of pain, fatigue, or difficulty thinking that lasts for more than 6 months after they finish treatment. One of the most common Lyme disease misdiagnoses is Rheumatoid Arthritis (RA), a chronic condition with less clear causes than Lyme disease. As many as 300,000 people will become infected with Lyme disease each year, with about 25% of those cases developing Lyme arthritis. Er is dan sprake van Lyme-artritis. InsideRadiology is a source of information about radiology produced especially for Australian health consumers. Serum serology, particularly IgG antibody response, is the key diagnostic test for Lyme arthritis. Patients with Lyme arthritis might notice that the joint that has been affected feels warm to the touch and will likely experience severe pain and swelling; particularly during movement. While much progress has been made in defining components of the immune response … Background Lyme disease is induced by the spirochete B. burgdorferi. A few had pain in other joints, such as the … Thus, there is overlap between Lyme arthritis treatment and the first-line option against rheumatoid arthritis, but Lyme arthritis usually requires a shorter duration of treatment, she said. Immun. Lyme disease typically presents with a significantly higher WBC concentration than does aseptic arthritis and a significantly lower concentration than that associated with septic arthritis. Similar to humans, horses are incidental, dead-end hosts for B. burgdorferi1. Medical science and other branches of science are biased and political. lyme arthritis radiology The constant inflammation of the synovium thickens the membrane lining and wears away the cartilage and ...|Arthritis is a general term that describes a family of medical conditions characterized by joint inflammation, pain, and stiffness. Striking in most instances suddenly it can be defined as a painful, swollen joint, that causes a stiffness similar to osteoarthritis. Lyme arthritis resolves with appropriate antimicrobial treatment in a majority of patients, but 10-20% of patients develop antibiotic-refractory Lyme arthritis with prolonged arthritis symptoms and treatment courses. More than 1100 documents describe diseases, anatomy, and radiologic findings. Lyme cases are on the increase, Dr. Arvikar said, so it's quite likely that if there is a relationship between Lyme and later autoimmune disease, those post-Lyme disorders will rise, too. 1.2 Introduction Arthritis related to Lyme disease can be a painful and disabling condition. The scope of this guideline includes prevention of Lyme disease, and the … 72: 4956-4965. Lyme arthritis is mono- or pauciarticular, generally involving large joints, most commonly the knee, and occurring months removed from the initial tick bite. Symptoms may come and go, sometimes returning years later. The aim of this study was to determine the diagnostic impact of routine Lyme serology in a French cohort of patients with recent-onset arthritis affecting at least 2 joints. Symptoms of Lyme disease in dogs can include soreness in the joints, similar to that of arthritis. Arthritis may, at times, present a mystifying appearance to the radiologist. About 10% of Lyme arthritis patients end up with a chronic form that doesn't go away with antibiotic treatment. Lyme arthritis, which is characterized by joint swelling and pain, is a condition that describes the most common advanced stage symptoms of Lyme disease, a bacterial infection spread by deer ticks to humans. But in about 15% of the cases, the arthritis appears before the psoriasis. by Mayla Hsu, Ph.D., Director of Research and Science, GLA. Ongeveer 1 op de 5 teken is besmet met Borrelia burgdorferi. PCR can be used as an adjunctive diagnostic test to identify DNA in synovial fluid but should not be the first lab test used. Antonyms for Lyme arthritis. Lyme Arthritis and Clinical Judgment. Jones KL, McHugh GA, Glickstein LJ, Steere AC. Demographics. arthri´tides ) inflammation of a joint. Introduction. A nymph is a baby tick, about the size of a poppy seed. SUMMARY: Lyme disease has a worldwide distribution and is the most common vector-borne disease in the United States. MRI features of Lyme arthritis in children. Rheumatoid arthritis 3. Researchers identify a missing piece of the Lyme disease puzzle. Lyme Arthritis Radiology Patient Leaflet Rheumatoid But in about 15% of the cases, the arthritis appears before the psoriasis. Patients who had persistent arthritis for at least 3 months after treatment with oral antibiotics or parenteral penicillin were given intravenous ceftriaxone for 2 weeks. Fig. musculoskeletal: Lyme arthritis; Radiographic features. MRI of Lyme arthritis of the knee shows findings in common with rheumatoid arthritis including bare area erosions, marrow edema, and synovial proliferation. adj., adj arthrit´ic. Arthritis Rheum 2009; 60:2174. The clinical manifestations, serological data, and radiographic findings of ten cases of Lyme arthritis in Germany are summarized. Based on the detection of B. burgdorferi sensu stricto DNA by PCR, clinicians diagnosed the man Lyme arthritis, a particular type of periprosthetic joint infection (PJI). 2.1 Classification of arthritis 1. Septic Arthritis Lyme Disease Lecture 2,687 views. The most common symptom was recurrent attacks of knee swelling. The arthritis incidence in the patients receiving Lyme vaccine occurred at the same rate as the background in unvaccinated individuals. & Pharmacother., 43 (1989) 401403 Elsevier, Paris 401 Dossier Lyme arthritis A. KAHAN', B. AMOR and C.J. Strong, outspoken and engaged volunteers will help us conquer arthritis. Treatment of mice with the neutrophil-depleting antibody RB6-8C5 results in early development of experimental Lyme arthritis via the recruitment of GR-1-polymorphonuclear leukocyte-like cells. However, even complex cases will usually yield to a logical and systematic approach. Steere AC. Patients with Lyme arthritis might notice that the joint that has been affected feels warm to the touch and will likely experience severe pain and swelling; particularly during movement. 8 In the setting of Lyme disease, joint aspirate typically has a cell count of 1,000 to 50,000 WBC cells/μL and is primarily composed of neutrophils, but the Gram stain may be negative. Lyme arthritis (LA) typically begins months after the initial tick exposure, and without antibiotic treatment, it often causes intermittent or persistent, monoarticular or oligoarticular arthritis, usually in 1 or 2 joints at a time, especially the knees, over a period of several years. In a new study, researchers have discovered a protein associated with Lyme disease that plays a role in triggering inflammation in Lyme arthritis patients by antagonising the patients’ immune system. Patients with rheumatoid arthritis are more likely to have radiological lumbar lesions. Lyme arthritis is condition known to be a late manifestation of Lyme disease. In the course of Lyme disease, one of the most common symptoms are problems with joints. I was bitten by a nymph, blacklegged deer tick in 2014. Incidence, clinical manifestations, and presentations vary by geography, season, and recreational habits. We investigated the possibility that manifestations of Lyme disease in certain hosts, such as arthritis and carditis, may be autoimmunity mediated due to molecular mimicry between the bacterium Borrelia burgdorferi and self-components. by Wayne Kuznar, Contributing Writer May 27, 2016 Blacklegged ticks are known to sometimes carry Borrelia burgdorferi, the bacteria that causes Lyme disease. Available for iPhone, iPad, Android, and Web. Findings from this latest study are a “testament to how unique this bacterium is — and how we need to keep working to understand more about what is going on behind the scenes in order to develop future diagnostics and treatments,” states Mari Davis, lead author on the paper. Put all your clothes in a hot dryer for 20 minutes to kill the ticks. Additional clinical and technical information for health professionals about radiology tests and image – guided treatments. Lyme arthritis results from Lyme disease, which is caused by an infection after a tick bite. Avoid dangerous arthritis drugs 711.26 Arthropathy in Behcets syndrome, lower leg convert 711.26 to ICD-10-CM. These symptoms include inflammation and muscle pain, sometimes known as Lyme arthritis, and can normally be treated with antibiotics and disease-modifying anti-rheumatic drugs (DMARDs) . Although Lyme arthritis usually resolves with antibiotic treatment for most patients, some continue to have joint swelling. Borrelia burgdorferi arthritis-associated locus Bbaa1 regulates Lyme arthritis and K/BxN serum transfer arthritis through intrinsic control of type I IFN production. Lyme disease is a newly recognized, multi-system disorder that may be associated with chronic arthritis. Lyme arthritis is almost never a … Virginia Tech researcher wins $661,216 grant to study Lyme arthritis. The Borelia bacterium has a large affinity to collagen structures. InsideRadiology is a source of information about radiology produced especially for Australian health consumers. Other joints, such as the ankle, shoulder, elbow or wrist, may be involved. Brown, C. R., V. A. Blaho, and C. M. Loiacono. Gout and Systemic Enzymes: Serapeptase 1 Jun. If clinical signs occur, they can include chronic weight loss, sporadic lameness, shifting leg lameness, The diagnostic criteria for JIA include disease onset before the age of 16 years, the presence of arthritis in one or more joints for at least 6 weeks, onset type defined by type of disease in the first 6 months of diagnosis (Box 137-1), and exclusion of other forms of juvenile arthritis. However, in Lyme disease the soreness comes on suddenly, and may move from one leg to another. We can only achieve these goals with your help. 1 synonym for Lyme arthritis: Lyme disease. It is the most common in the joints of the feet, ankles, usually a big … 9 Various studies pointed to swelling and inflammation primarily of large synovial joints, 10 with the knee and ankle the 2 most affected sites. The law of parsimony. Arthritic pain can resemble mono or oligoarticular JIA. Abstract. Lyme disease and rheumatoid arthritis share some characteristics, such as joint pain and a feeling of unwellness. Physiology and medicine are always full of exceptions to virtually every rule. Lyme Arthritis. Small joints, like those found in the hands, are hardly ever affected. Dit is een bacterie (spirocheet) die teken soms bij zich dragen en die via een tekenbeet het lichaam binnen kan komen. Lyme arthritis usually causes mild to moderate pain and swelling around these joints. OBJECTIVE: To test treatment regimens for Lyme arthritis. A gene family called the human leukocyte antigen (HLA) complex are thought to be associated with antibiotic-resistant Lyme arthritis. Lyme arthritis: [ ahr-thri´tis ] (pl. Lyme arthritis, which is characterized by joint swelling and pain, is a condition that describes the most common advanced stage symptoms of Lyme disease, a bacterial infection spread by deer ticks to humans. Methods We performed an ancillary study of a French prospective … Experimental Lyme arthritis is an inflammatory arthritis caused by infection of mice with the spirochete, Borrelia burgdorferi. Of 25 patients with severe arthritic manifestations the most frequent radiographic finding was knee joint effusion. –. 2007;56(12):4216-4225. Lyme disease, and in particular Lyme-related arthritis and joint pain, is personal for me. We present the MRI features of Lyme disease of the hip in a 4-year-old boy who presented with hip pain and was found to have Lyme disease by Western blot. It contains: Information about radiology tests and procedures that you or a family member may require. Arthritis. The diagnosis was based on criteria established by the Musculoskeletal Infection Society and the Infectious Disease Society of America (IDSA). Pattern approach. Lyme Arthritis answers are found in the Johns Hopkins ABX Guide powered by Unbound Medicine. Small joints, like those found in the hands, are hardly ever affected. Based on the detection of B. burgdorferi sensu stricto DNA by PCR, clinicians diagnosed the man Lyme arthritis, a particular type of periprosthetic joint infection (PJI). J Clin Invest 2020; 130:2148. Intracranial MR imaging findings in patients with Lyme disease are rare 2. LYME ARTHRITIS. The overall prevalence is 0.5-1% and the disease is 2-3 times more common in women 1. Awareness of these characteristic MRI features may avoid …. However, their treatment is very different. Ook kunnen in deze fase de gewrichten ontstoken raken. I can neither afford to go see a LLMD, nor make the trip, as none are less than a 1,000 mile round trip for me - so I doubt I will ever have a dx of Lyme arthritis. Now, before I let you go, I want to mention one thing. Seronegative arthritis (ankylosing spondylitis, reactive arthritis, psoriatic arthritis, enteropathic… The elbow is rarely the first joint to present with symptoms. Lyme arthritis is seen in Lyme disease, which affects the large joints and is seen after a prolonged period of untreated Lyme disease. Arthritis is not a single disease, but a group of over 100 diseases that cause pain and limit movement. Radiographic hallmarks. Clinical Features of Late Lyme Disease • Arthritis •Diagnosis • Objective evidence of joint inflammation + serology • Synovial fluid analysis: cell count, crystals, culture • Establish presence of inflammatory arthritis (i.e. Important study identifies the Borrelia burgdorferi peptidoglycan as an immunogen likely to cause Lyme arthritis in some patients. Learn to spot the signs of this common tick-borne disease. The Horror of Lyme Arthritis Explained. Lyme arthritis more often than not occurs in the knees, but it can also affect other large joints, including the shoulder, elbow, ankle, jaw, wrist, and hip. Researchers think the chronic arthritis of Lyme disease may be linked to how the … Lyme arthritis, caused by the tick‐borne spirochete Borrelia burgdorferi (1), typically causes intermittent or persistent arthritis in a few large joints, especially the knee, for several years ().Treatment recommendations have changed over time. CHORUS is a hypertext medical reference. Limited triple-phase Tc-99m MDP bone imaging of the wrists and hands with delayed whole-body images was performed in a patient with Lyme arthritis. Lyme arthritis diagnosis. It is only assumed that I have Lyme arthritis, as I have been told I have no arthritis 'markers' in my blood. Methods. Additional clinical and technical information for health professionals about radiology tests and image – guided treatments. Lyme arthritis is caused in Europe by three main pathogenic species of Borrelia burgdorferi sensu lato: Borrelia burgdorferi sensu stricto, Borrelia garinii , and Borrelia afzelii . Analysis of Borrelia burgdorferi genotypes in patients with Lyme arthritis: High frequency of ribosomal RNA intergenic spacer type 1 strains in antibiotic-refractory arthritis. Lyme arthritis is an oligoarthritis most commonly affecting the knees. Imaging studies are not required for the evaluation of Lyme arthritis. However, plain films may show effusion. Ultrasound or MRI can be used to evaluate for synovitis and tendinitis, and for diagnosis of Baker’s cysts. Radiographic erosions are rare in Lyme arthritis. Introduction: Lyme disease is the most common tick borne illness in the United States. No rapid laboratory test reliably identifies serologic markers of borellial infection, and there is considerable overlap in the clinical, laboratory, and radiographic presentation of children with Lyme arthritis and those with other acute arthritides.

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